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CSO Statement on guidance to protect research during a second wave of COVID-19 activity

Research, development and innovation are an integral and vital part of our NHS. The Chief Scientist Office (CSO) has been working with colleagues across the NHS to support the restarting of research paused due to the COVID-19 pandemic. This work has been guided by the Restart Framework developed by the National Institute for Health Research (NIHR) in consultation with the Devolved Administrations and

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Participants being sought to take part in national COVID-19 trial

PRINCIPLE is a nationwide clinical trial to find COVID-19 treatments for the over 50s that can be taken at home Led by Oxford University, the Platform Randomised trial of Interventions against COVID-19 in older peoPLE (PRINCIPLE) trial is testing pre-existing drugs for older patients in the community who show signs of the disease. It aims to slow or halt the p...

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Applied Research on Longer-Term Effects of COVID-19 Infection

The Chief Scientist Office (CSO) are launching a call for applied research proposals designed to improve understanding of the longer-term effects of COVID-19 infection on physical and mental health and wellbeing in Scotland, and/or research with the aim of developing effective clinical interventions to support recovery and rehabilitation from COVID-19 infection. Remit Studies within remit would include: the epidemiology of, or clinical evaluation of diagnostic, prognostic an...

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Over 250,000 volunteers now registered for new COVID-19 vaccine trials as recruitment begins for Novavax study

Ten thousand UK volunteers have been invited to join the world’s first phase three COVID-19 vaccine study to test the effectiveness of the new Novavax COVID-19 vaccine This comes as the number of people in the UK who have signed up to take part in COVID-19 research through the NHS COVID-19 vaccine research registry hits 250,000.   Participants aged between 18-85 years will help test the safety and effectiveness of a new COVID-19 vaccine, developed by US biotechnolog...

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10,000 NHS Scotland staff to take part in COVID-19 study

SIREN (Sarscov2 Immunity & REinfection EvaluatioN) is a UK-wide study testing 100,000 health workers, which will provide information on immunity from and prevalence of COVID-19 infection. The primary objective of the study is to determine whether the presence of COVID-19 antibodies is associated with a reduction in the subsequent risk of re-infection over the next year. The data will also be used to estimate the prevalence of COVID19 infection in healthcare workers by region....

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NHS Research Scotland Restarting Research Survey

A new patient survey has been launched by NHS Research Scotland to capture confidence levels of patients returning to participate in NHS research.  Whilst COVID-19 research continues to be delivered across NHS health boards; work is also underway to restore the diverse portfolio of health and social care research Scotland offered before the pandemic. The survey will uncover issues and concerns patients may have, and how best to reassure and manage patient recruitment to c...

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Over 100,000 volunteers now registered for COVID-19 vaccine trials

As the number of people registered to take part in COVID-19 vaccine trials has now topped 100,000, we are encouraging others to follow their lead to help speed up efforts to discover safe and effective vaccines. The NHS COVID-19 vaccine research registry will help large numbers of people to be recruited into the trials over the coming months, potentially leading to effective vaccines being identifie...

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Landmark MND trial opens in Dundee

The groundbreaking motor neurone disease clinical drugs trial, MND-SMART, has today opened to participants in NHS Tayside. This is the trial’s second UK centre. The trial will be based at the Clinical Research Centre at Ninewells hospital in Dundee and will welcome participants to the trial from across NHS Tayside. Motor Neurone Disease (MND), also known as amyotrophic lateral sclerosis or ALS, is a progressive condition that causes muscle to waste away. It occurs...

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Guidance on health and social care research projects for educational purposes - update

In March 2020 the Health Research Authority (HRA) and devolved administrations (DA's) announced the suspension of reviewing applications for individual undergraduate and master’s student projects until further notice, while the urgent review of COVID-19 studies took place. This was also due to the significant pressure on the NHS/Health and Social Care (HSC), limiting its ability to participate in research studies unrelated to COVID-19. As the lockdown eases, the HRA...

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Make It Public transparency strategy launches

The new strategy marks a step-change in making health research findings available to the public  The Health Research Authority (HRA) has today (Thursday 30 July) launched a new strategy to ensure information about all health and social care research – including COVID-19 research - is made publicly available to benefit patients, researchers and policymakers. The strategy is delivered by the HRA in partnership with N...

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